yes, you can create email alerts based on response time. there are default alerts out of the box. See the 6 minute video on alerts to understand how to customize the email message Network Performance Monitor (NPM) Training - YouTube
you can apply thresholds to all devices, override it manually for each device / multiple devices, or let the product baseline the statistics & automatically set the thresholds. See the blog below for some screenshots on independent node thresholds and baselines